Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection
Chagas disease: protecting from chronic parasitic disease An amalgamation of parasitic proteins may be the first effective vaccine against the as yet untreatable chronic phase of Chagas disease. The infliction, caused by the parasite Trypanosoma cruzi (T. cruzi), is the world’s leading cause of infe...
Main Authors: | Andrés Sanchez Alberti, Augusto E. Bivona, Natacha Cerny, Kai Schulze, Sebastian Weißmann, Thomas Ebensen, Celina Morales, Angel M. Padilla, Silvia I. Cazorla, Rick L. Tarleton, Carlos A. Guzmán, Emilio L. Malchiodi |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-04-01
|
Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-017-0010-z |
Similar Items
-
Trypanosoma cruzi 80 kDa prolyl oligopeptidase (Tc80) as a novel immunogen for Chagas disease vaccine.
by: Augusto E Bivona, et al.
Published: (2018-03-01) -
Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against Trypanosoma cruzi
by: Andrés Sanchez Alberti, et al.
Published: (2020-02-01) -
Cruzipain and Its Physiological Inhibitor, Chagasin, as a DNA-Based Therapeutic Vaccine Against Trypanosoma cruzi
by: Natacha Cerny, et al.
Published: (2020-10-01) -
THE ROLE OF IMMUNOLOGY IN COMBATING TRYPANOSOMA CRUZI INFECTION AND CHAGAS DISEASE
by: Rick L. Tarleton
Published: (2013-01-01) -
Activity of Estafietin and Analogues on <i>Trypanosoma cruzi</i> and <i>Leishmania braziliensis</i>
by: Valeria P. Sülsen, et al.
Published: (2019-03-01)