Long-Term Environmental Hypoxia Exposure and Haematopoietic Prolyl Hydroxylase-1 Deletion Do Not Impact Experimental Crohn’s Like Ileitis

Environmental hypoxia and hypoxia-induced signalling in the gut influence inflammatory bowel disease pathogenesis, however data is limited to colitis. Hence, we investigated the effect of environmental hypoxia and immune cell-specific deletion of oxygen sensor prolyl hydroxylase (PHD) 1 in a Crohn’s...

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Bibliographic Details
Main Authors: Cara De Galan, Martine De Vos, Pieter Hindryckx, Debby Laukens, Sophie Van Welden
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/10/9/887