Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial–mesenchymal transition by regulating HIF-1α via miR-138

Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial–mesenchymal transition by regulating HIF-1α via miR-138

Long non-coding RNA LINC00152 had been reported as an oncogene in gastric and hepatocellular cancer. In this study, we show that LINC00152 is overexpressed in gallbladder cancer (GBC) tissue samples and cell lines. The high LINC00152 levels correlated negatively with the overall survival time in GBC...

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Bibliographic Details
Main Authors: Qiang Cai, Zhenqiang Wang, Shouhua Wang, Mingzhe Weng, Di Zhou, Chen Li, Jiandong Wang, Erzhen Chen, Zhiwei Quan
Format: Article
Language:English
Published: The Royal Society 2017-01-01
Series:Open Biology
Subjects:
long non-coding rna linc00152
gallbladder cancer
metastasis
epithelial–mesenchymal transition
hif-1α
mir-138
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160247

Internet

https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160247

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