The Pharmacokinetics of Raloxifene and Its Interaction with Apigenin in Rat

The Pharmacokinetics of Raloxifene and Its Interaction with Apigenin in Rat

Purpose: Raloxifene is a selective estrogen receptor modulator which is structurally similar to tamoxifen. As flavonoids can interact with raloxifene in vitro, we evaluated the in vivo pharmacokinetics of raloxifene in rats when co-administered with apigenin. Methods: The pharmacokinetics of raloxif...

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Bibliographic Details
Main Authors: Ming Hu, Yan Chen, Xiaobin Jia, Jinyan Wang, Jian Chen
Format: Article
Language:English
Published: MDPI AG 2010-11-01
Series:Molecules
Subjects:
raloxifene
apigenin
pharmacokinetics
interaction
flavonoid
rats
Online Access:http://www.mdpi.com/1420-3049/15/11/8478/

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http://www.mdpi.com/1420-3049/15/11/8478/

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