Regulatory role of IL-1R8 in immunity and disease

Regulatory role of IL-1R8 in immunity and disease

Interleukin-1 receptor family members (ILRs) and Toll Like Receptors (TLRs) are characterized by the presence of a conserved intracellular domain, the Toll/IL-1resistance (TIR) domain and are key players in immunity and inflammation. ILR and TLR signalling is tightly regulated at different levels. A...

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Bibliographic Details
Main Authors: Martina eMolgora, Isabella eBarajon, Alberto eMantovani, Cecilia eGarlanda
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Immunology
Subjects:
Infection
Inflammation
Interleukin-1
cytokine
Toll like receptors
inflammation-associated cancer
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00149/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00149/full

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