Qingjie Fuzheng Granule suppresses lymphangiogenesis in colorectal cancer via the VEGF-C/VEGFR-3 dependent PI3K/AKT pathway

Qingjie Fuzheng Granule suppresses lymphangiogenesis in colorectal cancer via the VEGF-C/VEGFR-3 dependent PI3K/AKT pathway

Scope: To investigate the effect of Qingjie Fuzheng Granule (QFG) on lymphangiogenesis and lymphatic metastasis in colorectal cancer. Methods: The effects of QFG on the expression and secretion of vascular endothelial growth factor-C (VEGF-C) in HCT-116 cells were investigated both in vitro and in v...

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Bibliographic Details
Main Authors: Bin Huang, Yao Lu, Mengxuan Gui, Jianhua Guan, Minghe Lin, Jinyan Zhao, Qianqian Mao, Jiumao Lin
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Colorectal cancer
Qingjie Fuzheng Granule
Lymphangiogenesis
VEGF-C
VEGFR-3
PI3K/AKT signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221001165

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http://www.sciencedirect.com/science/article/pii/S0753332221001165

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