The impact of cHS4 insulators on DNA transposon vector mobilization and silencing in retinal pigment epithelium cells.

DNA transposons have become important vectors for efficient non-viral integration of transgenes into genomic DNA. The Sleeping Beauty (SB), piggyBac (PB), and Tol2 transposable elements have distinct biological properties and currently represent the most promising transposon systems for animal trans...

Full description

Bibliographic Details
Main Authors: Nynne Sharma, Anne Kruse Hollensen, Rasmus O Bak, Nicklas Heine Staunstrup, Lisbeth Dahl Schrøder, Jacob Giehm Mikkelsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23110238/?tool=EBI