Development of 3D Chromatin Texture Analysis Using Confocal Laser Scanning Microscopy

Introduction: Analysis of nuclear texture features as a measure of nuclear chromatin changes has been proven to be useful when measured on thin (5–6 μm) tissue sections using conventional 2D bright field microscopy. The drawback of this approach is that most nuclei are not intact because of those th...

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Bibliographic Details
Main Authors: André Huisman, Lennert S. Ploeger, Hub F. J. Dullens, Neal Poulin, William E. Grizzle, Paul J. van Diest
Format: Article
Language:English
Published: Hindawi Limited 2005-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2005/494605