Examining the pathogenesis of breast cancer using a novel agent-based model of mammary ductal epithelium dynamics.

The study of the pathogenesis of breast cancer is challenged by the long time-course of the disease process and the multi-factorial nature of generating oncogenic insults. The characterization of the longitudinal pathogenesis of malignant transformation from baseline normal breast duct epithelial dy...

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Bibliographic Details
Main Authors: Joaquin Chapa, Ryan J Bourgo, Geoffrey L Greene, Swati Kulkarni, Gary An
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660364?pdf=render