Modelling amyotrophic lateral sclerosis: progress and possibilities

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that primarily affects the motor system and presents with progressive muscle weakness. Most patients survive for only 2-5 years after disease onset, often due to failure of the respiratory muscles. ALS is a familial disease in ∼10%...

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Bibliographic Details
Main Authors: Philip Van Damme, Wim Robberecht, Ludo Van Den Bosch
Format: Article
Language:English
Published: The Company of Biologists 2017-05-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/10/5/537