Maternal LPS exposure during pregnancy impairs testicular development, steroidogenesis and spermatogenesis in male offspring.

Lipopolysaccharide (LPS) is associated with adverse developmental outcomes including embryonic resorption, fetal death, congenital teratogenesis and fetal growth retardation. Here, we explored the effects of maternal LPS exposure during pregnancy on testicular development, steroidogenesis and sperma...

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Bibliographic Details
Main Authors: Hua Wang, Lu-Lu Yang, Yong-Fang Hu, Bi-Wei Wang, Yin-Yin Huang, Cheng Zhang, Yuan-Hua Chen, De-Xiang Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4177809?pdf=render