Imprinted Gene Expression and Function of the Dopa Decarboxylase Gene in the Developing Heart
Dopa decarboxylase (DDC) synthesizes serotonin in the developing mouse heart where it is encoded by Ddc_exon1a, a tissue-specific paternally expressed imprinted gene. Ddc_exon1a shares an imprinting control region (ICR) with the imprinted, maternally expressed (outside of the central nervous system)...
Main Authors: | Adam R. Prickett, Bertille Montibus, Nikolaos Barkas, Samuele M. Amante, Maurício M. Franco, Michael Cowley, William Puszyk, Matthew F. Shannon, Melita D. Irving, Marta Madon-Simon, Andrew Ward, Reiner Schulz, H. Scott Baldwin, Rebecca J. Oakey |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-06-01
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Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2021.676543/full |
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