The influence of HLA on HIV-associated neurocognitive impairment in Anhui, China.

The influence of HLA on HIV-associated neurocognitive impairment in Anhui, China.

HLA-DR*04 was identified as a predictor of HIV-Associated neurocognitive disorder (HAND), low CD4 T-cell responses to HIV, and low plasma HIV RNA levels in a U.S. cohort. We hypothesized that low CD4 T-cell activation leads to poor immune control of HIV in the CNS, predisposing to HAND, but also pro...

Full description

Bibliographic Details
Main Authors: Rachel D Schrier, Saurabh Gupta, Patricia Riggs, Lucette A Cysique, Scott Letendre, Hua Jin, Stephen A Spector, Kumud K Singh, Tanya Wolfson, Zunyou Wu, Kun Xue Hong, Xin Yu, Chuan Shi, Robert K Heaton, HNRC Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3365058?pdf=render

Internet

http://europepmc.org/articles/PMC3365058?pdf=render

Similar Items