The Skeletal Muscle Emerges as a New Disease Target in Amyotrophic Lateral Sclerosis

The Skeletal Muscle Emerges as a New Disease Target in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that leads to progressive degeneration of motor neurons (MNs) and severe muscle atrophy without effective treatment. Most research on ALS has been focused on the study of MNs and supporting cells of the central nervous system....

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Bibliographic Details
Main Authors: Oihane Pikatza-Menoio, Amaia Elicegui, Xabier Bengoetxea, Neia Naldaiz-Gastesi, Adolfo López de Munain, Gorka Gerenu, Francisco Javier Gil-Bea, Sonia Alonso-Martín
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Journal of Personalized Medicine
Subjects:
ALS
skeletal muscle
neuromuscular junction
metabolism
vesicles
distal axonopathy
Online Access:https://www.mdpi.com/2075-4426/11/7/671

Internet

https://www.mdpi.com/2075-4426/11/7/671

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