Combined activity of COX-1 and COX-2 is increased in non-neoplastic colonic mucosa from colorectal neoplasia patients

Combined activity of COX-1 and COX-2 is increased in non-neoplastic colonic mucosa from colorectal neoplasia patients

Abstract Background Cyclooxygenase (COX) activity is increased in endoscopic normal colonic mucosa from patients with colorectal neoplasia (CRN). COX-2 is thought to be the predominant COX isozyme involved in neoplasia. Meanwhile, relative contributions of COX-1 and COX-2 isoforms are unknown. Knowl...

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Bibliographic Details
Main Authors: Thorbjørn Søren Rønn Jensen, Badar Mahmood, Morten Bach Damm, Marie Balslev Backe, Mattias Salling Dahllöf, Steen Seier Poulsen, Mark Berner Hansen, Niels Bindslev
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Gastroenterology
Subjects:
Short circuit current (SCC)
Cyclooxygenase
Endoscopic
Biopsy
Carcinogenesis
Tuft cells
Online Access:http://link.springer.com/article/10.1186/s12876-018-0759-1

Internet

http://link.springer.com/article/10.1186/s12876-018-0759-1

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