Decidualisation and placentation defects are a major cause of age-related reproductive decline
Advanced maternal age has been associated with lower reproductive success and higher risk of pregnancy complications. Here the authors show that maternal ageing-related embryonic abnormalities in mouse are caused by decidualisation and placentation defects that can be rescued by transferring the emb...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2017-09-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-00308-x |