NFAT2 overexpression suppresses the malignancy of hepatocellular carcinoma through inducing Egr2 expression

NFAT2 overexpression suppresses the malignancy of hepatocellular carcinoma through inducing Egr2 expression

Abstract Background Nuclear factor of activated T cells 2 (NFAT2) has been reported to regulate the development and malignancy of few tumors. In this study, we aimed to explore the effect of NFAT2 expression on cell fate of HepG2 cell and its potential mechanisms. Methods Firstly, the pcDNA3.1-NFAT2...

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Bibliographic Details
Main Authors: Jian Wang, Yamin Zhang, Lei Liu, Zilin Cui, Rui Shi, Jiancun Hou, Zirong Liu, Long Yang, Lianjiang Wang, Yang Li
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Cancer
Subjects:
NFAT2
HepG2 cells
Hepatocellular carcinoma
Cancer malignancy
Online Access:http://link.springer.com/article/10.1186/s12885-020-07474-0

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http://link.springer.com/article/10.1186/s12885-020-07474-0

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