Action of Clathrodin and Analogues on Voltage-Gated Sodium Channels

Clathrodin is a marine alkaloid and believed to be a modulator of voltage-gated sodium (NaV) channels. Since there is an urgent need for small molecule NaV channel ligands as novel therapeutics, clathrodin could represent an interesting lead compound. Therefore, clathrodin was reinvestigated for its...

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Bibliographic Details
Main Authors: Steve Peigneur, Aleš Žula, Nace Zidar, Fiona Chan-Porter, Robert Kirby, David Madge, Janez Ilaš, Danijel Kikelj, Jan Tytgat
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/12/4/2132