The protective effect of infliximab against carbon tetrachloride-induced acute lung injury

The protective effect of infliximab against carbon tetrachloride-induced acute lung injury

Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-α). We aimed to investigate whether Ib has a protective effect on CCl4 induced lung injury. Materials and Methods:Rats were divided into control, CCl4, and C...

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Bibliographic Details
Main Authors: Aysel Kurt, Levent Tumkaya, Suleyman Yuce, Hasan Turut, Medine Cumhur Cure, Ibrahim Sehitoglu, Yildiray Kalkan, Gokhan Pusuroglu, Erkan Cure
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Carbon tetrachloride
Infliximab
Nitric oxide
Pulmonary toxicity
Oxidative stress
Online Access:http://ijbms.mums.ac.ir/article_7138_3039f66c559f977304a83ed093dac0e2.pdf

Internet

http://ijbms.mums.ac.ir/article_7138_3039f66c559f977304a83ed093dac0e2.pdf

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