Cardioprotective Effects of Combined Therapy with Hyperbaric Oxygen and Diltiazem Pretreatment on Myocardial Ischemia-Reperfusion Injury in Rats

Cardioprotective Effects of Combined Therapy with Hyperbaric Oxygen and Diltiazem Pretreatment on Myocardial Ischemia-Reperfusion Injury in Rats

Background/Aims: In this study, we examined whether the combination of hyperbaric oxygen (HBO) and diltiazem therapy provided a cardioprotective effect on myocardial ischemia-reperfusion injury (MIRI) rat model. Methods: Sixty healthy Sprague-Dawley rats were randomly divided into sham, IR, diltiaze...

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Bibliographic Details
Main Authors: Chunxia Chen, Wan Chen, Zhihuan Nong, Yuan Ma, Shaoling Qiu, Guangwei Wu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Hyperbaric oxygen
Diltiazem
Myocardial ischemia-reperfusion injury
Nitric oxide
Apoptosis
Online Access:http://www.karger.com/Article/FullText/445561

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http://www.karger.com/Article/FullText/445561

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