Granulocyte Macrophage Colony-Stimulating FactorâActivated CD39+/CD73+ Murine Monocytes Modulate Intestinal Inflammation via Induction of Regulatory T CellsSummary

Background & Aims: Granulocyte macrophage colony-stimulating factor (GM-CSF) treatment induces clinical response in patients with active Crohnâs disease. To explore whether monocytes mediate GM-CSF effects in vivo, we used a mouse model of chronic colitis induced by dextran sulfate sodium (DSS)...

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Bibliographic Details
Main Authors: Toni Weinhage, Jan Däbritz, Anne Brockhausen, Timo Wirth, Markus Brückner, Michael Belz, Dirk Foell, Georg Varga
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X15000843