Atheroprotective Vaccination with MHC-II Restricted Peptides from ApoB-100

Background: Subsets of CD4+ T-cells have been proposed to serve differential roles in the development of atherosclerosis. Some T-cell types are atherogenic (T-helper type 1), while others are thought to be protective (regulatory T-cells). Lineage commitment toward one type of helper T-cell versus an...

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Bibliographic Details
Main Authors: Kevin Yee-Bien Tse, Ayelet eGonen, John eSidney, Hui eOuyang, Joseph L Witztum, Alessandro eSette, Harley Y Tse, Klaus eLey
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00493/full