Clinical Grade Production of Wilms’ Tumor-1 Loaded Cord Blood-Derived Dendritic Cells to Prevent Relapse in Pediatric AML After Cord Blood Transplantation

Clinical Grade Production of Wilms’ Tumor-1 Loaded Cord Blood-Derived Dendritic Cells to Prevent Relapse in Pediatric AML After Cord Blood Transplantation

Hematopoietic cell transplantation (HCT) is a last resort, potentially curative treatment option for pediatric patients with refractory acute myeloid leukemia (AML). Cord blood transplantation (CBT) results in less relapses and less graft-versus-host disease when compared to other sources. Neverthel...

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Bibliographic Details
Main Authors: Maud Plantinga, Vania Lo Presti, Colin G. de Haar, Ester Dünnebach, Alejandro Madrigal, Caroline A. Lindemans, Jaap Jan Boelens, Stefan Nierkens
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
vaccine
cord blood
immunotherapy
transplantation
good manufacturing practice
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.559152/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.559152/full

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