Original Fluorescent Ligand-Based Assays Open New Perspectives in G-Protein Coupled Receptor Drug Screening

The identification of new drugs exhibiting reduced adverse side-effects constitutes a great challenge for the next decade. Various steps are needed to screen for good ligand candidates and one of them is the evaluation of their binding properties. New strategies based on fluorescence measurement con...

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Bibliographic Details
Main Authors: Thierry Durroux, Jurriaan M. Zwier, Eric Trinquet, Orestis Faklaris, Martin Cottet, Jean-Philippe Pin
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/4/1/202/