MicroRNAs signatures, bioinformatics analysis of miRNAs, miRNA mimics and antagonists, and miRNA therapeutics in osteosarcoma

MicroRNAs signatures, bioinformatics analysis of miRNAs, miRNA mimics and antagonists, and miRNA therapeutics in osteosarcoma

Abstract MicroRNAs (miRNAs) involved in key signaling pathways and aggressive phenotypes of osteosarcoma (OS) was discussed, including PI3K/AKT/MTOR, MTOR AND RAF-1 signaling, tumor suppressor P53- linked miRNAs, NOTCH- related miRNAs, miRNA -15/16 cluster, apoptosis related miRNAs, invasion-metasta...

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Bibliographic Details
Main Authors: Babak Otoukesh, Mehdi Abbasi, Habib-o-Lah Gorgani, Hossein Farahini, Mehdi Moghtadaei, Bahram Boddouhi, Peyman Kaghazian, Shayan Hosseinzadeh, Atefe Alaee
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cancer Cell International
Subjects:
MicroRNAs
Osteosarcoma
Targets
Therapy
Online Access:http://link.springer.com/article/10.1186/s12935-020-01342-4

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http://link.springer.com/article/10.1186/s12935-020-01342-4

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