G790del mutation in DSC2 alone is insufficient to develop the pathogenesis of ARVC in a mouse model

G790del mutation in DSC2 alone is insufficient to develop the pathogenesis of ARVC in a mouse model

Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart disease that causes heart failure and/or sudden cardiac death. Several desmosomal genes (DSC2, PKG, PKP2, DSP, and RyR2) are thought to be the causative gene involved in ARVC. Out of them, DSC2 mutations account...

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Main Authors: Yoriomi Hamada, Takeshi Yamamoto, Yoshihide Nakamura, Yoko Sufu-Shimizu, Takuma Nanno, Masakazu Fukuda, Makoto Ono, Tesuro Oda, Shinichi Okuda, Takeshi Ueyama, Shigeki Kobayashi, Masafumi Yano
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580819302481

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http://www.sciencedirect.com/science/article/pii/S2405580819302481

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