The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions

The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions

Background: Human papillomavirus (HPV) has long been proposed as a cofactor in the pathogenesis of cutaneous squamous cell carcinoma (cSCC). More recently, the striking clinico-pathological features of cSCCs that complicate treatment of metastatic melanoma with inhibitors targeting BRAF mutations (B...

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Bibliographic Details
Main Authors: Karin J. Purdie, Charlotte M. Proby, Hasan Rizvi, Heather Griffin, John Doorbar, Mary Sommerlad, Mariet C. Feltkamp, Els Van der Meijden, Gareth J. Inman, Andrew P. South, Irene M. Leigh, Catherine A. Harwood
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Microbiology
Subjects:
human polyomaviruses
human papillomaviruses
cutaneous squamous cell carcinomas
BRAF inhibitors
melanoma
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01806/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01806/full

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