Decreased hematocrit-to-viscosity ratio and increased lactate dehydrogenase level in patients with sickle cell anemia and recurrent leg ulcers.

Leg ulcer is a disabling complication in patients with sickle cell anemia (SCA) but the exact pathophysiological mechanisms are unknown. The aim of this study was to identify the hematological and hemorheological alterations associated with recurrent leg ulcers. Sixty-two SCA patients who never expe...

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Bibliographic Details
Main Authors: Philippe Connes, Yann Lamarre, Marie-Dominique Hardy-Dessources, Nathalie Lemonne, Xavier Waltz, Danièle Mougenel, Martin Mukisi-Mukaza, Marie-Laure Lalanne-Mistrih, Vanessa Tarer, Benoit Tressières, Maryse Etienne-Julan, Marc Romana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3817120?pdf=render