PEAβ Triggers Cognitive Decline and Amyloid Burden in a Novel Mouse Model of Alzheimer’s Disease

PEAβ Triggers Cognitive Decline and Amyloid Burden in a Novel Mouse Model of Alzheimer’s Disease

Understanding the physiopathology of Alzheimer’s disease (AD) has improved substantially based on studies of mouse models mimicking at least one aspect of the disease. Many transgenic lines have been established, leading to amyloidosis but lacking neurodegeneration. The aim of the current study was...

Full description

Bibliographic Details
Main Authors: Luana Cristina Camargo, Michael Schöneck, Nivethini Sangarapillai, Dominik Honold, N. Jon Shah, Karl-Josef Langen, Dieter Willbold, Janine Kutzsche, Sarah Schemmert, Antje Willuweit
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
transgenic mice
behavioral tests
amyloid plaques
Alzheimer´s disease
mouse model
amyloidosis
Online Access:https://www.mdpi.com/1422-0067/22/13/7062

Internet

https://www.mdpi.com/1422-0067/22/13/7062

Similar Items