Tissue and host species-specific transcriptional changes in models of experimental visceral leishmaniasis [version 2; referees: 3 approved, 1 approved with reservations]

Background: Human visceral leishmaniasis, caused by infection with Leishmania donovani or L. infantum, is a potentially fatal disease affecting 50,000-90,000 people yearly in 75 disease endemic countries, with more than 20,000 deaths reported. Experimental models of infection play a major role in un...

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Bibliographic Details
Main Authors: Helen Ashwin, Karin Seifert, Sarah Forrester, Najmeeyah Brown, Sandy MacDonald, Sally James, Dimitris Lagos, Jon Timmis, Jeremy C Mottram, Simon L. Croft, Paul M. Kaye
Format: Article
Language:English
Published: Wellcome 2019-01-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/3-135/v2