Novel Insights into the Antagonistic Effects of Losartan against Angiotensin II/AGTR1 Signaling in Glioblastoma Cells

Novel Insights into the Antagonistic Effects of Losartan against Angiotensin II/AGTR1 Signaling in Glioblastoma Cells

New avenues for glioblastoma therapy are required due to the limited mortality benefit of the current treatments. The renin-angiotensin system (RAS) exhibits local actions and works as a paracrine system in different tissues and tumors, including glioma. The glioblastoma cell lines U-87 MG and T98G...

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Bibliographic Details
Main Authors: Salvatore Panza, Rocco Malivindi, Amanda Caruso, Umberto Russo, Francesca Giordano, Balázs Győrffy, Luca Gelsomino, Francesca De Amicis, Ines Barone, Francesca Luisa Conforti, Cinzia Giordano, Daniela Bonofiglio, Stefania Catalano, Sebastiano Andò
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
glioblastoma
Angiotensin II
Angiotensin II type I receptor
renin-angiotensin system
aromatase
Losartan
Online Access:https://www.mdpi.com/2072-6694/13/18/4555

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https://www.mdpi.com/2072-6694/13/18/4555

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