Dynamic evaluation of the immune infiltrate and immune function genes as predictive markers for neoadjuvant chemotherapy in hormone receptor positive, HER2 negative breast cancer

Dynamic evaluation of the immune infiltrate and immune function genes as predictive markers for neoadjuvant chemotherapy in hormone receptor positive, HER2 negative breast cancer

Gene expression (GE) signatures and Tumor Infiltrating Lymphocytes (TIL) enumeration are predictive for response to neoadjuvant chemotherapy in HR- and in HER2+ breast cancer, but data are conflicting in HR+/HER2- disease. This study aimed to explore their predictive value in this subset, measured b...

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Bibliographic Details
Main Authors: Alexios Matikas, John Lövrot, Anna Ramberg, Margareta Eriksson, Therese Lindsten, Tobias Lekberg, Ingrid Hedenfalk, Niklas Loman, Jonas Bergh, Thomas Hatschek, Ann Erlandsson, Theodoros Foukakis
Format: Article
Language:English
Published: Taylor & Francis Group 2018-09-01
Series:OncoImmunology
Subjects:
biomarker
breast cancer
gene expression
predictive
tumor infiltrating lymphocytes
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1466017

Internet

http://dx.doi.org/10.1080/2162402X.2018.1466017

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