Low-Intensity MR-Guided Focused Ultrasound Mediated Disruption of the Blood-Brain Barrier for Intracranial Metastatic Diseases

Low-Intensity MR-Guided Focused Ultrasound Mediated Disruption of the Blood-Brain Barrier for Intracranial Metastatic Diseases

Low-intensity MR-guided focused ultrasound in combination with intravenously injected microbubbles is a promising platform for drug delivery to the central nervous system past the blood-brain barrier. The blood-brain barrier is a key bottleneck for cancer therapeutics via limited inter- and intracel...

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Bibliographic Details
Main Authors: Ying Meng, Suganth Suppiah, Shanan Surendrakumar, Luca Bigioni, Nir Lipsman
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Oncology
Subjects:
focused ultrasound (MRgFUS)
blood brain barrier (BBB) disruption
neuro-oncology–surgical
intracranial metastatic disease
drug deliver-system
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00338/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00338/full

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