Compromised base excision repair pathway in Mycobacterium tuberculosis imparts superior adaptability in the host.

Tuberculosis caused by Mycobacterium tuberculosis (Mtb) is a significant public health concern, exacerbated by the emergence of drug-resistant TB. To combat the host's dynamic environment, Mtb encodes multiple DNA repair enzymes that play a critical role in maintaining genomic integrity. Mtb po...

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Bibliographic Details
Main Authors: Saba Naz, Shruti Dabral, Sathya Narayanan Nagarajan, Divya Arora, Lakshya Veer Singh, Pradeep Kumar, Yogendra Singh, Dhiraj Kumar, Umesh Varshney, Vinay Kumar Nandicoori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009452