A G-Quadruplex Structure in the Promoter Region of CLIC4 Functions as a Regulatory Element for Gene Expression

A G-Quadruplex Structure in the Promoter Region of CLIC4 Functions as a Regulatory Element for Gene Expression

The differential transcriptional expression of CLIC4 between tumor cells and the surrounding stroma during cancer progression has been suggested to have a tumor-promoting effect. However, little is known about the transcriptional regulation of CLIC4. To better understand how this gene is regulated,...

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Bibliographic Details
Main Authors: Mu-Ching Huang, I-Te Chu, Zi-Fu Wang, Steven Lin, Ta-Chau Chang, Chin-Tin Chen
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
G-quadruplex
transcriptional regulation
promoter
CRISPR/Cas9
Online Access:http://www.mdpi.com/1422-0067/19/9/2678

Internet

http://www.mdpi.com/1422-0067/19/9/2678

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