The Crystal Structure of the <i>Plasmodium falciparum</i> PdxK Provides an Experimental Model for Pro-Drug Activation

Pyridoxine/pyridoxal kinase (PdxK), belongs to the ribokinase family and is involved in the vitamin B6 salvage pathway by phosphorylating 5-pyridoxal (PL) into an active form. In the human malaria parasite, <i>Plasmodium falciparum</i>, <i>Pf</i>PdxK functions to salvage vita...

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Bibliographic Details
Main Authors: Kai Gao, Wenjia Wang, Thales Kronenberger, Carsten Wrenger, Matthew R. Groves
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Crystals
Subjects:
pt3
pt5
Online Access:https://www.mdpi.com/2073-4352/9/10/534