Preemptive Tolerogenic Delivery of Donor Antigens for Permanent Allogeneic Islet Graft Protection
We have previously developed a robust regimen for tolerance induction in murine models of islet cell transplantation using pre- and posttransplant infusions of donor splenocytes (SPs) treated with a chemical cross-linker ethylcarbodiimide (ECDI). However, the requirement for large numbers of fresh d...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2015-06-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368914X681027 |