The Kil peptide of bacteriophage λ blocks Escherichia coli cytokinesis via ZipA-dependent inhibition of FtsZ assembly.

Assembly of the essential, tubulin-like FtsZ protein into a ring-shaped structure at the nascent division site determines the timing and position of cytokinesis in most bacteria and serves as a scaffold for recruitment of the cell division machinery. Here we report that expression of bacteriophage λ...

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Bibliographic Details
Main Authors: Daniel P Haeusser, Marina Hoashi, Anna Weaver, Nathan Brown, James Pan, James A Sawitzke, Lynn C Thomason, Donald L Court, William Margolin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3961180?pdf=render