Functional link between mitochondria and Rnr3, the minor catalytic subunit of yeast ribonucleotide reductase

Ribonucleotide reductase (RNR) is an essential holoenzyme required for de novo synthesis of dNTPs. The Saccharomyces cerevisiae genome encodes for two catalytic subunits, Rnr1 and Rnr3. While Rnr1 is required for DNA replication and DNA damage repair, the function(s) of Rnr3 is unknown. Here, we sho...

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Bibliographic Details
Main Authors: Isaac Corcoles-Saez, Jean-Luc Ferat, Michael Costanzo, Charles M. Boone, Rita S. Cha
Format: Article
Language:English
Published: Shared Science Publishers OG 2019-05-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/2019a-corcoles-saez-microbial-cell/