Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis

Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis

Abstract Background Psoriasis is a chronic inflammatory autoimmune skin disorder. Several studies suggested psoriasis to be a complex multifactorial disease, but the exact triggering factor is yet to be determined. Evidences suggest that in addition to genetic factors, epigenetic reprogramming is al...

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Bibliographic Details
Main Authors: Aditi Chandra, Swapan Senapati, Sudipta Roy, Gobinda Chatterjee, Raghunath Chatterjee
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Clinical Epigenetics
Subjects:
Differentially methylated probes
Methylation-sensitive PCR
Bisulfite cloning and sequencing
Gene expression
Histopathology of psoriasis
Munro’s microabscess
Online Access:http://link.springer.com/article/10.1186/s13148-018-0541-9

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http://link.springer.com/article/10.1186/s13148-018-0541-9

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