Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation

Oxidative stress is involved in the development of carotid body (CB) chemosensory potentiation and systemic hypertension induced by chronic intermittent hypoxia (CIH), the main feature of obstructive sleep apnea. We tested whether peroxynitrite (ONOO−), a highly reactive nitrogen species, is involve...

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Bibliographic Details
Main Authors: Esteban A. Moya, Paulina Arias, Carlos Varela, María P. Oyarce, Rodrigo Del Rio, Rodrigo Iturriaga
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/9802136