Genome-Wide Scan for Visceral Leishmaniasis in Mixed-Breed Dogs Identifies Candidate Genes Involved in T Helper Cells and Macrophage Signaling.

Genome-Wide Scan for Visceral Leishmaniasis in Mixed-Breed Dogs Identifies Candidate Genes Involved in T Helper Cells and Macrophage Signaling.

We conducted a genome-wide scan for visceral leishmaniasis in mixed-breed dogs from a highly endemic area in Brazil using 149,648 single nucleotide polymorphism (SNP) markers genotyped in 20 cases and 28 controls. Using a mixed model approach, we found two candidate loci on canine autosomes 1 and 2....

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Bibliographic Details
Main Authors: Yuri T Utsunomiya, Érica S Ribeiro, Amanda P N Quintal, Juliano R Sangalli, Valquiria R Gazola, Henrique B Paula, Cristiana M Trinconi, Valéria M F Lima, Silvia H V Perri, Jeremy F Taylor, Robert D Schnabel, Tad S Sonstegard, José F Garcia, Cáris M Nunes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4562658?pdf=render

Internet

http://europepmc.org/articles/PMC4562658?pdf=render

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