Characterization of the Interaction between Gallic Acid and Lysozyme by Molecular Dynamics Simulation and Optical Spectroscopy

Characterization of the Interaction between Gallic Acid and Lysozyme by Molecular Dynamics Simulation and Optical Spectroscopy

The binding interaction between gallic acid (GA) and lysozyme (LYS) was investigated and compared by molecular dynamics (MD) simulation and spectral techniques. The results from spectroscopy indicate that GA binds to LYS to generate a static complex. The binding constants and thermodynamic parameter...

Full description

Bibliographic Details
Main Authors: Minzhong Zhan, Ming Guo, Yanke Jiang, Xiaomeng Wang
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:International Journal of Molecular Sciences
Subjects:
gallic acid
lysozyme
molecular dynamics simulation
spectroscopic techniques
MM-PBSA method
Online Access:http://www.mdpi.com/1422-0067/16/7/14786

Internet

http://www.mdpi.com/1422-0067/16/7/14786

Similar Items