Lysyl oxidase polymorphisms and susceptibility to osteosarcoma.

Despite the knowledge of many genetic alterations present in osteosarcoma, the complexity of this disease precludes placing its biology into a simple conceptual framework. Lysyl oxidase (LOX) catalyzes the cross-linking of elastin and collagen, which is essential for the structural integrity and fun...

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Bibliographic Details
Main Authors: Yang Liu, Bitao Lv, Zhimin He, Yujia Zhou, Carrie Han, Guodong Shi, Rui Gao, Ce Wang, Lili Yang, Haihan Song, Wen Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3402457?pdf=render