Integrating influenza antigenic dynamics with molecular evolution

Integrating influenza antigenic dynamics with molecular evolution

Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between influenza strains using the hemagglutination inhibition (HI) assay...

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Bibliographic Details
Main Authors: Trevor Bedford, Marc A Suchard, Philippe Lemey, Gytis Dudas, Victoria Gregory, Alan J Hay, John W McCauley, Colin A Russell, Derek J Smith, Andrew Rambaut
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-02-01
Series:eLife
Subjects:
influenza
evolution
antigenic cartography
phylogenetic
Bayesian inference
multidimensional scaling
Online Access:https://elifesciences.org/articles/01914

Internet

https://elifesciences.org/articles/01914

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