Differences between RNA and DNA due to RNA editing in temporal lobe epilepsy

Differences between RNA and DNA due to RNA editing in temporal lobe epilepsy

To investigate whether alterations in RNA editing (an enzymatic base-specific change to the RNA sequence during primary transcript formation from DNA) of neurotransmitter receptor genes and of transmembrane ion channel genes play a role in human temporal lobe epilepsy (TLE), this exploratory study a...

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Bibliographic Details
Main Authors: Heinz Krestel, Simon Raffel, Marec von Lehe, Caroline Jagella, Susanna Moskau-Hartmann, Albert Becker, Christian E. Elger, Peter H. Seeburg, Arto Nirkko
Format: Article
Language:English
Published: Elsevier 2013-08-01
Series:Neurobiology of Disease
Subjects:
Pharmacotherapy-resistant epilepsy
All-or-none RNA editing
Kv1.1
Clinical parameter correlation
GluA3
Estimated effect size
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113001204

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http://www.sciencedirect.com/science/article/pii/S0969996113001204

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