Michel's Transport Medium as an Alternative to Liquid Nitrogen for PCR Analysis of Skin Biopsy Specimens

Formalin fixation and paraffin embedding are standard procedures for histopathological diagnosis and allow long-term archiving of tissue specimens. The cross-linking properties of formalin cause fragmentation of nucleic acids and reduce the sensitivity of PCR analysis. Michel's medium is a well...

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Bibliographic Details
Main Authors: Logeina Boraiy, Lionel Fontao
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Dermatopathology
Subjects:
PCR
DNA
Online Access:http://www.karger.com/Article/FullText/368347