Phosphorylated peptides from Antarctic krill (Euphausia superba) ameliorated osteoporosis by activation of osteogenesis-related MAPKs and PI3K/AKT/GSK-3β pathways in dexamethasone-treated mice

Phosphorylated peptides from Antarctic krill (Euphausia superba) ameliorated osteoporosis by activation of osteogenesis-related MAPKs and PI3K/AKT/GSK-3β pathways in dexamethasone-treated mice

In this study, the effects of phosphorylated peptides from Antarctic krill (PP-AKP) on osteoporosis induced by dexamethasone were investigated in vivo. Results showed that PP-AKP significantly improved bone turnover status, reduced bone loss and degeneration of microarchitecture, in addition to acce...

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Bibliographic Details
Main Authors: Lihua Han, Xiangzhao Mao, Kai Wang, Yuanyuan Li, Meihui Zhao, Jingfeng Wang, Changhu Xue
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Journal of Functional Foods
Subjects:
Antarctic krill
Phosphorylated peptides
Bone formation
Dexamethasone
MAPKs
PI3K/AKT/GSK-3β
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618303001

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http://www.sciencedirect.com/science/article/pii/S1756464618303001

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