Reductive modification of genetically encoded 3-nitrotyrosine sites in alpha synuclein expressed in E.coli

Tyrosine nitration is a post-translational protein modification relevant to various pathophysiological processes. Chemical nitration procedures have been used to generate and study nitrated proteins, but these methods regularly lead to modifications at other amino acid residues. A novel strategy emp...

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Bibliographic Details
Main Authors: Hanne R. Gerding, Christiaan Karreman, Andreas Daiber, Johannes Delp, Daniel Hammler, Martin Mex, Stefan Schildknecht, Marcel Leist
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719305580