Impact of the B Cell Growth Factor APRIL on the Qualitative and Immunological Characteristics of Atherosclerotic Plaques.

Studies on the role of B lymphocytes in atherosclerosis development, have yielded contradictory results. Whereas B lymphocyte-deficiency aggravates atherosclerosis in mice; depletion of mature B lymphocytes reduces atherosclerosis. These observations led to the notion that distinct B lymphocyte subs...

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Bibliographic Details
Main Authors: Sophie J Bernelot Moens, Sander I van Leuven, Kang H Zheng, Stefan R Havik, Miranda V Versloot, Leonie M van Duivenvoorde, Michael Hahne, Erik S G Stroes, Dominique L Baeten, Anouk A J Hamers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5098816?pdf=render